Figure 1. Correlation among ALC, NLR and CYT in BC patients. (A) The treatment and sampling protocol. (B) The correlation between ALC and NLR in advanced BC patients. Left, before treatment (n, number of samples); middle, during treatment (n, number of samples); right, the correlation between the ALC-increase ratio and NLR-decrease ratio (n, number of patients). (C) The correlation between ALC and NLR in advanced BC patients according to the anticancer drugs. n, number of samples. (D) The correlation between ALC, NLR and CYT score in BC patients. The cutoff values of ALC, NLR and CYT scores were 1700, 1.75 and 31.56, respectively. n, number of patients. ALC and NLR were expressed relative to the level prior to treatment with each line of therapy (BS=1.0). *p<0.05. ALC, Absolute lymphocyte count; NLR, neutrophil-to-lymphocyte ratio; CYT, cytolytic activity; BC, breast cancer; BS, baseline.