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Research ArticleArticle

CRY1 Regulates Chemoresistance in Association With NANOG by Inhibiting Apoptosis via STAT3 Pathway in Patients With Cervical Cancer

GWAN HEE HAN, JULIE KIM, HEE YUN, HANBYOUL CHO, JOON-YONG CHUNG, JAE-HOON KIM and STEPHEN M. HEWITT
Cancer Genomics & Proteomics November 2021, 18 (6) 699-713; DOI: https://doi.org/10.21873/cgp.20291
GWAN HEE HAN
1Department of Obstetrics and Gynecology, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea;
2Yonsei University Graduate School, Seoul, Republic of Korea;
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JULIE KIM
3Weill Cornell Medical College, New York, NY, U.S.A.;
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HEE YUN
4Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea;
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HANBYOUL CHO
5Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Republic of Korea;
6Institute of Women’s Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea;
7Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, U.S.A.
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  • For correspondence: hanbyoul{at}yuhs.ac
JOON-YONG CHUNG
7Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, U.S.A.
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JAE-HOON KIM
5Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Republic of Korea;
6Institute of Women’s Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea;
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STEPHEN M. HEWITT
7Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, U.S.A.
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Article Information

vol. 18 no. 6 699-713
DOI 
https://doi.org/10.21873/cgp.20291
PMID 
34697063

Published By 
International Institute of Anticancer Research
Print ISSN 
1109-6535
Online ISSN 
1790-6245
History 
  • Received July 20, 2021
  • Revision received August 12, 2021
  • Accepted August 23, 2021
  • Published online October 25, 2021.

Copyright & License 
Copyright © 2021 The Author(s). Published by the International Institute of Anticancer Research.

Author Information

  1. GWAN HEE HAN1,2,
  2. JULIE KIM3,
  3. HEE YUN4,
  4. HANBYOUL CHO5,6,7⇑,
  5. JOON-YONG CHUNG7,
  6. JAE-HOON KIM5,6 and
  7. STEPHEN M. HEWITT7
  1. 1Department of Obstetrics and Gynecology, Kyung Hee University Hospital at Gangdong, Seoul, Republic of Korea;
  2. 2Yonsei University Graduate School, Seoul, Republic of Korea;
  3. 3Weill Cornell Medical College, New York, NY, U.S.A.;
  4. 4Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea;
  5. 5Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Republic of Korea;
  6. 6Institute of Women’s Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea;
  7. 7Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, U.S.A.
  1. Correspondence to: Hanbyoul Cho, MD, Ph.D., Professor, Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-Ro, Gangnam-Gu, Seoul 06273, Republic of Korea. Tel: +82 220193430, Fax: +82 234628209, e-mail: hanbyoul{at}yuhs.ac
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CRY1 Regulates Chemoresistance in Association With NANOG by Inhibiting Apoptosis via STAT3 Pathway in Patients With Cervical Cancer
GWAN HEE HAN, JULIE KIM, HEE YUN, HANBYOUL CHO, JOON-YONG CHUNG, JAE-HOON KIM, STEPHEN M. HEWITT
Cancer Genomics & Proteomics Nov 2021, 18 (6) 699-713; DOI: 10.21873/cgp.20291

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CRY1 Regulates Chemoresistance in Association With NANOG by Inhibiting Apoptosis via STAT3 Pathway in Patients With Cervical Cancer
GWAN HEE HAN, JULIE KIM, HEE YUN, HANBYOUL CHO, JOON-YONG CHUNG, JAE-HOON KIM, STEPHEN M. HEWITT
Cancer Genomics & Proteomics Nov 2021, 18 (6) 699-713; DOI: 10.21873/cgp.20291
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Keywords

  • CRY1
  • NANOG
  • apoptosis
  • Cervical cancer
  • biomarker
  • chemoradiation response
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