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Research Article
Open Access

Significant Association Between the MiR146a Genotypes and Susceptibility to Childhood Acute Lymphoblastic Leukemia in Taiwan

JEN-SHENG PEI, WEN-SHIN CHANG, PEI-CHEN HSU, CHAO-CHUN CHEN, YU-TING CHIN, TAI-LIN HUANG, YUAN-NIAN HSU, CHIEN-CHUNG KUO, YUN-CHI WANG, CHIA-WEN TSAI, CHI-LI GONG and DA-TIAN BAU
Cancer Genomics & Proteomics March 2020, 17 (2) 175-180; DOI: https://doi.org/10.21873/cgp.20178
JEN-SHENG PEI
1Department of Pediatrics, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, R.O.C.
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WEN-SHIN CHANG
2Terry Fox Cancer Research Laboratory, China Medical University Hospital, Taichung, Taiwan, R.O.C.
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PEI-CHEN HSU
1Department of Pediatrics, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, R.O.C.
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CHAO-CHUN CHEN
1Department of Pediatrics, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, R.O.C.
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YU-TING CHIN
2Terry Fox Cancer Research Laboratory, China Medical University Hospital, Taichung, Taiwan, R.O.C.
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TAI-LIN HUANG
2Terry Fox Cancer Research Laboratory, China Medical University Hospital, Taichung, Taiwan, R.O.C.
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YUAN-NIAN HSU
3Department of Family Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, R.O.C.
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CHIEN-CHUNG KUO
4Department of Pediatric Orthopedics, China Medical University Hospital, Taichung, Taiwan, R.O.C.
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YUN-CHI WANG
2Terry Fox Cancer Research Laboratory, China Medical University Hospital, Taichung, Taiwan, R.O.C.
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CHIA-WEN TSAI
2Terry Fox Cancer Research Laboratory, China Medical University Hospital, Taichung, Taiwan, R.O.C.
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  • For correspondence: datian@mail.cmuh.org.tw artbau2@gmail.com
CHI-LI GONG
2Terry Fox Cancer Research Laboratory, China Medical University Hospital, Taichung, Taiwan, R.O.C.
5Department of Physiology, China Medical University, Taichung, Taiwan, R.O.C.
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  • For correspondence: datian@mail.cmuh.org.tw artbau2@gmail.com
DA-TIAN BAU
2Terry Fox Cancer Research Laboratory, China Medical University Hospital, Taichung, Taiwan, R.O.C.
6Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.
7Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan, R.O.C.
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  • For correspondence: datian@mail.cmuh.org.tw artbau2@gmail.com
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Article Information

vol. 17 no. 2 175-180
DOI 
https://doi.org/10.21873/cgp.20178
PubMed 
32108040

Published By 
International Institute of Anticancer Research
Print ISSN 
1109-6535
Online ISSN 
1790-6245
History 
  • Received January 3, 2020
  • Revision received January 18, 2020
  • Accepted January 23, 2020
  • Published online February 27, 2020.

Copyright & Usage 
Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved

Author Information

  1. JEN-SHENG PEI1,*,
  2. WEN-SHIN CHANG2,*,
  3. PEI-CHEN HSU1,*,
  4. CHAO-CHUN CHEN1,
  5. YU-TING CHIN2,
  6. TAI-LIN HUANG2,
  7. YUAN-NIAN HSU3,
  8. CHIEN-CHUNG KUO4,
  9. YUN-CHI WANG2,
  10. CHIA-WEN TSAI2⇑,
  11. CHI-LI GONG2,5⇑ and
  12. DA-TIAN BAU2,6,7⇑
  1. 1Department of Pediatrics, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, R.O.C.
  2. 2Terry Fox Cancer Research Laboratory, China Medical University Hospital, Taichung, Taiwan, R.O.C.
  3. 3Department of Family Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, R.O.C.
  4. 4Department of Pediatric Orthopedics, China Medical University Hospital, Taichung, Taiwan, R.O.C.
  5. 5Department of Physiology, China Medical University, Taichung, Taiwan, R.O.C.
  6. 6Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan, R.O.C.
  7. 7Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan, R.O.C.
  1. Correspondence: Da-Tian Bau, Chi-Li Gong and Chia-Wen Tsai, Terry Fox Cancer Research Laboratory, Translational Medicine Research Center, China Medical University Hospital, 2 Yuh-Der Road, Taichung, 404 Taiwan, R.O.C. Tel: +886 422053366 (Ext. 5805), e-mail: datian{at}mail.cmuh.org.tw; artbau2{at}gmail.com
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Cancer Genomics - Proteomics: 17 (2)
Cancer Genomics & Proteomics
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Significant Association Between the MiR146a Genotypes and Susceptibility to Childhood Acute Lymphoblastic Leukemia in Taiwan
JEN-SHENG PEI, WEN-SHIN CHANG, PEI-CHEN HSU, CHAO-CHUN CHEN, YU-TING CHIN, TAI-LIN HUANG, YUAN-NIAN HSU, CHIEN-CHUNG KUO, YUN-CHI WANG, CHIA-WEN TSAI, CHI-LI GONG, DA-TIAN BAU
Cancer Genomics & Proteomics Mar 2020, 17 (2) 175-180; DOI: 10.21873/cgp.20178

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Significant Association Between the MiR146a Genotypes and Susceptibility to Childhood Acute Lymphoblastic Leukemia in Taiwan
JEN-SHENG PEI, WEN-SHIN CHANG, PEI-CHEN HSU, CHAO-CHUN CHEN, YU-TING CHIN, TAI-LIN HUANG, YUAN-NIAN HSU, CHIEN-CHUNG KUO, YUN-CHI WANG, CHIA-WEN TSAI, CHI-LI GONG, DA-TIAN BAU
Cancer Genomics & Proteomics Mar 2020, 17 (2) 175-180; DOI: 10.21873/cgp.20178
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Keywords

  • acute lymphoblastic leukemia
  • case–control study
  • genotype
  • miR146a
  • polymorphism
  • Taiwan
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