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Evaluation of Podoplanin Expression in Hepatocellular Carcinoma Using RNAscope and Immunohistochemistry – A Preliminary Report

ANDREEA CIOCA, ANCA MARIA CIMPEAN, RALUCA AMALIA CEAUSU, VALERIA TARLUI, ALINA TOMA, IRINA MARIN and MARIUS RAICA
Cancer Genomics & Proteomics September 2017, 14 (5) 383-387;
ANDREEA CIOCA
1Department of Histology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
2Angiogenesis Research Center, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
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  • For correspondence: cioca_andre{at}yahoo.com
ANCA MARIA CIMPEAN
1Department of Histology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
2Angiogenesis Research Center, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
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RALUCA AMALIA CEAUSU
1Department of Histology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
2Angiogenesis Research Center, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
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VALERIA TARLUI
2Angiogenesis Research Center, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
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ALINA TOMA
2Angiogenesis Research Center, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
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IRINA MARIN
3Department of Pathology, Sheba Medical Center, Tel-Hashomer, Israel
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MARIUS RAICA
1Department of Histology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
2Angiogenesis Research Center, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
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    Figure 1.

    A: Podoplanin (PDPN) immunohistochemistry in showing cytoplasmic staining of tumour cells at low magnification (×40) and at high magnification (inset; ×100), score 2+. B-D: PDPN mRNA signal was identified in tumour cells as multiple small brown dots as indicated by red arrow: score 1, with 0-1 dots/cell, (B); score 2, 4-10 dots/cell (C); score 4, >10 dots/cell and more than 10% positive cells with dot clusters (D).

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Cancer Genomics & Proteomics
Vol. 14, Issue 5
September-October 2017
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Evaluation of Podoplanin Expression in Hepatocellular Carcinoma Using RNAscope and Immunohistochemistry – A Preliminary Report
ANDREEA CIOCA, ANCA MARIA CIMPEAN, RALUCA AMALIA CEAUSU, VALERIA TARLUI, ALINA TOMA, IRINA MARIN, MARIUS RAICA
Cancer Genomics & Proteomics Sep 2017, 14 (5) 383-387;

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Evaluation of Podoplanin Expression in Hepatocellular Carcinoma Using RNAscope and Immunohistochemistry – A Preliminary Report
ANDREEA CIOCA, ANCA MARIA CIMPEAN, RALUCA AMALIA CEAUSU, VALERIA TARLUI, ALINA TOMA, IRINA MARIN, MARIUS RAICA
Cancer Genomics & Proteomics Sep 2017, 14 (5) 383-387;
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Keywords

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