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Research ArticleExperimental Studies
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Low Levels of Microsatellite Instability at Simple Repeated Sequences Commonly Occur in Human Hepatocellular Carcinoma

CLAIRE GOUMARD, CHRISTELE DESBOIS-MOUTHON, DOMINIQUE WENDUM, CLAIRE CALMEL, FATIHA MERABTENE, OLIVIER SCATTON and FRANÇOISE PRAZ
Cancer Genomics & Proteomics September 2017, 14 (5) 329-339;
CLAIRE GOUMARD
1Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Centre de Recherche Saint-Antoine (CRSA), Paris, France
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CHRISTELE DESBOIS-MOUTHON
1Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Centre de Recherche Saint-Antoine (CRSA), Paris, France
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DOMINIQUE WENDUM
1Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Centre de Recherche Saint-Antoine (CRSA), Paris, France
2APHP, Hôpital Saint-Antoine, Service d'Anatomie Pathologique, Paris, France
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CLAIRE CALMEL
1Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Centre de Recherche Saint-Antoine (CRSA), Paris, France
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FATIHA MERABTENE
1Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Centre de Recherche Saint-Antoine (CRSA), Paris, France
3Plateforme d'Histomorphologie Saint-Antoine, UMS 30, Paris, France
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OLIVIER SCATTON
1Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Centre de Recherche Saint-Antoine (CRSA), Paris, France
4APHP, Hôpital Saint-Antoine, Service de Chirurgie Hépatobiliaire, Paris, France
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FRANÇOISE PRAZ
1Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Centre de Recherche Saint-Antoine (CRSA), Paris, France
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  • For correspondence: francoise.praz@upmc.fr
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    Figure 1.

    Examples of pentaplex PCR of mononucleotide repeats. (1a) Typical profile of a tumor devoid of microsatellite instability; (1b) HCC case displaying an atypical profile at the BAT25 marker, (1c) typical profile of an MSI colorectal tumor.

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Cancer Genomics - Proteomics: 14 (5)
Cancer Genomics & Proteomics
Vol. 14, Issue 5
September-October 2017
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Low Levels of Microsatellite Instability at Simple Repeated Sequences Commonly Occur in Human Hepatocellular Carcinoma
CLAIRE GOUMARD, CHRISTELE DESBOIS-MOUTHON, DOMINIQUE WENDUM, CLAIRE CALMEL, FATIHA MERABTENE, OLIVIER SCATTON, FRANÇOISE PRAZ
Cancer Genomics & Proteomics Sep 2017, 14 (5) 329-339;

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Low Levels of Microsatellite Instability at Simple Repeated Sequences Commonly Occur in Human Hepatocellular Carcinoma
CLAIRE GOUMARD, CHRISTELE DESBOIS-MOUTHON, DOMINIQUE WENDUM, CLAIRE CALMEL, FATIHA MERABTENE, OLIVIER SCATTON, FRANÇOISE PRAZ
Cancer Genomics & Proteomics Sep 2017, 14 (5) 329-339;
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Keywords

  • Hepatocellular carcinoma
  • microsatellite instability
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  • inflammation
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